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    Question

    Each question below has two blanks, which is indicating

    that something has been omitted. Choose the most suitable option indicating the words that can be used to fill up the blanks in the sentences to make them meaningfully complete. The second difficulty in assessing the systematic review was its inclusion of __________studies. While the methodology of systematic reviews of randomized controlled trials is______ to a high degree, this is not the case for systematic reviews of observational studies. 
    A Observational, Uniform Correct Answer Incorrect Answer
    B Abstract, Unnecessary Correct Answer Incorrect Answer
    C Imaginative, Diverse Correct Answer Incorrect Answer
    D Intuitive, Variable Correct Answer Incorrect Answer
    E Assumed, Liable Correct Answer Incorrect Answer

    Solution

    The sentence discusses the difficulty in evaluating a systematic review based on the types of studies it includes.

    • The first blank refers to a type of study that presents a "second difficulty." Observational studies are a category of research that often have varying methodologies and can be more prone to bias than randomized controlled trials. This inherent variability makes them harder to assess in a systematic review.
    • Uniform means remaining the same in all cases and at all times; consistent. This word accurately describes the standardized and highly controlled methodology of RCTs, which makes them easier to assess in a systematic review.
    Therefore, the inclusion of observational studies presents a difficulty because the methodology for reviewing them is not as uniform as it is for randomized controlled trials. Liable means being legally responsible for something, often an obligation or debt. Variable means something that is subject to change or can be altered

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