Question

In the following questions, a sentence is given with a highlighted phrase in it. The highlighted phrase may/may not be grammatically correct. Choose the best alternative to replace the highlighted phrase so as to make the sentence grammatically and contextually correct. If no replacement is required, choose option E as your answer. Researchers noted that patient recovery rates improved significant when the new daily therapy was administered under strict medical supervision.

A significantly where the new daily therapy was administered
B significant while the new daily therapy was administered
C significantly when the new daily therapy was administered
D more significant when the new daily therapy was administered
E No replacement required
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