Question

The health risks and its _______ on the global economic ecosystem has been the major priority agenda for all APEC economies this year.

The following questions consist of a single sentence with one blank only. You are given four words, out of which you have to pick the correct word, which will make the sentence meaningfully correct and complete. The option with the correct word will be your answer. If none of the answers seems appropriate, choose option 5.
A Issue
B Impact
C Discussion
D Announcement
E None of these
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