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    Question

    When DNA replication starts

    A the phosphodiester bonds between the adjacent nucleotide break Correct Answer Incorrect Answer
    B the bonds between the nitrogen base and deoxyribose sugar break Correct Answer Incorrect Answer
    C the leading strand produces Okazaki fragments Correct Answer Incorrect Answer
    D the hydrogen bonds between the nucleotides of two strands break Correct Answer Incorrect Answer

    Solution

    When DNA replication starts, the hydrogen bonds between the nucleotides of the two DNA strands break. This separation of the two DNA strands is a crucial step in the initiation of DNA replication, as it allows the DNA polymerase enzyme to access the exposed single strands and begin synthesizing complementary DNA strands.

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