Question

Which of the following organic compounds undergo nucleophilic substitution reaction most easily?

Q: Answer-Which of the following organic compounds undergo nucleophilic substitution reaction most easily?

The rate of a nucleophilic substitution reaction depends heavily on how easily the leaving group halogen atom can depart from the molecule. In alkyl halides like CHX X halogen, the leaving group ability follows this trend I - Br - Cl - F - This is because Iodide I is the largest and least basic halide ion, and thus it leaves most easily. Fluoride F is small and strongly bonded to carbon, making it a poor leaving group.