Question
Which enzyme is responsible for removing RNA primers
during DNA replication?Solution
During DNA replication, RNA primers are required to initiate the synthesis of new DNA strands. These primers are later removed and replaced with DNA. DNA polymerase I in prokaryotes (like E. coli) is responsible for removing RNA primers and replacing them with DNA using its 5' → 3' exonuclease activity. This enzyme also has polymerase activity to fill the gaps left after primer removal.
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