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    Question

    Which of the following molecular interactions is the

    strongest in stabilizing the tertiary structure of proteins?
    A Hydrogen bonds Correct Answer Incorrect Answer
    B Disulfide bonds Correct Answer Incorrect Answer
    C Hydrophobic interactions Correct Answer Incorrect Answer
    D Ionic bonds Correct Answer Incorrect Answer

    Solution

    Disulfide bonds are covalent bonds formed between two cysteine residues through oxidation of their sulfhydryl (-SH) groups. These bonds provide strong structural stability to proteins, particularly extracellular proteins like insulin and keratin. Key Points: • Disulfide bonds form between two cysteine residues (-SH → -S-S-). • Stronger than hydrogen bonds and ionic interactions. • Play a crucial role in protein folding and stability. • Found in extracellular and secretory proteins.

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