Question
Which year did Shimon Sakaguchi make his key discovery
about immune tolerance?Solution
In 1995, Shimon Sakaguchi made a crucial discovery revealing that immune tolerance is a complex process involving regulatory T cells, which prevent the immune system from attacking the body’s own cells. His work laid the groundwork for future discoveries in autoimmune disease prevention.
If 4   x     4           7          15        38.5
Then,  ( x + 1) ( x - 1) = ?
...32 63 121 ? 453 889
...12 3 15 ? 153 756
...40 41 86 ? 1084 5445
...32    54    98    186    ?     714
8 6 2 ? -1 9.5
...24 25 46 ? 572 2885
...64   66   70   73   ?   86
15     12    ?     9     21     6
...3, 4, 10, 33, 136, ?, 4116