Question

I.            The effects of global warming on plants and animals are expected to be widespread and ___________.
II.            Without help, Rachel will not be able to overcome the _________________ challenges of her drug addiction.

In these questions two sentences are given with blanks in them and you have to choose an appropriate word from the given options that can fill both the sentences making them grammatically and meaningfully complete.
A retreat
B doctrine
C Profound
D Crisis
E None of these
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