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    Question

    In Krebs Cycle, the initial step in the oxidation of

    pyruvate is its conversion to 
    A Acetyl-CoA Correct Answer Incorrect Answer
    B Malic Acid Correct Answer Incorrect Answer
    C Succinic Acid Correct Answer Incorrect Answer
    D Citric Acid Correct Answer Incorrect Answer

    Solution

    Pyruvate—three carbons—is converted to acetyl CoA, a two-carbon molecule attached to coenzyme A. A molecule of coenzyme A is a necessary reactant for this reaction, which releases a molecule of carbon dioxide and reduces a NAD+ to NADH.

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