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S1 is a series of 5 consecutive prime numbers starting from the second lowest prime number. S2 is a series of 5 consecutive odd numbers whose first term is equal to the fourth term of S1. S3 is a series of 5 consecutive even numbers with average 6. What is the difference between the greatest term of S3 to the middle term of S2?

A 2

B -2

C -5

D 5

E -3

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